Eight patients tested for multimeric analysis.

(A) Multimer analysis of plasma vWF from the propositus of each family. (B) Comparison of sample from the propositus C1 with type 2A (F751C) and type 2M (I662F) plasma vWF. The plasma samples were electrophoresed in 1% agarose gels and visualized using ¹²⁵I-labeled anti-vWF pAbs. (C) Analysis of triplet structure of plasma vWF multimers. The samples from propositi C1 and D1 were electrophoresed in 2.5% agarose gels and visualized using anti-vWF pAbs labeled with alkaline phosphatase. NP indicates normal plasma.