Increased IL-3 in mice with CML-like disease originates from the recipient.

Total circulating IL-3 (A) and GM-CSF (B) levels were determined by ELISA (see “Materials and methods”) in leukemic mice from transplants with the indicated genotypes of donors and recipients (donors indicated first, then recipients). The values for wild-type mice transplanted with wild-type vector-transduced (MSCVneo) or BCR/ABL-transduced (BCR/ABL WT to WT) marrow are reproduced from Figure 1 for comparison. Error bars indicate SE.