Fig. 2.
Fig. 2. SCH66336 slowed the proliferation of BCR/ABL-BaF3 cells in liquid culture. / BCR/ABL-BaF3 cells were split into medium containing the indicated concentration of SCH66336, and cell numbers were measured for 4 days. SCH66336 caused a dose-dependent reduction in proliferation with an IC50 of 0.5 to 1 μM. BCR/ABL-BaF3 cells expressing dominant-negative Ras show no perceptible reduction in proliferation (data not shown).

SCH66336 slowed the proliferation of BCR/ABL-BaF3 cells in liquid culture.

BCR/ABL-BaF3 cells were split into medium containing the indicated concentration of SCH66336, and cell numbers were measured for 4 days. SCH66336 caused a dose-dependent reduction in proliferation with an IC50 of 0.5 to 1 μM. BCR/ABL-BaF3 cells expressing dominant-negative Ras show no perceptible reduction in proliferation (data not shown).

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