Fig. 6.
Methylation-specific PCR for the p15INAK4Bpromoter in normal bone marrow cells and leukemia samples.
Three of the 4 AML cases gave the methylation-specific PCR band, whereas normal bone marrow cells and CML cases showed only the unmethylated DNA-specific band. M-primer indicates primers specific for methylated DNA; U-primers, primers specific for unmethylated DNA.