Fig. 2. Sickle RBC oxygen equilibrium curves in the presence of NS3623. / Human SS cells were incubated with NS3623 (0, 10, 50, and 200 μM). HbS-hemoglobin oxygen saturation (percentage, ordinate axis) was measured in intact cells as a function of oxygen partial pressure (abscissa axis). Hill coefficients and oxygen half-saturation mean pressures ± SDs (n = 4) are indicated on the individual curves.
Fig. 2.

Sickle RBC oxygen equilibrium curves in the presence of NS3623.

Human SS cells were incubated with NS3623 (0, 10, 50, and 200 μM). HbS-hemoglobin oxygen saturation (percentage, ordinate axis) was measured in intact cells as a function of oxygen partial pressure (abscissa axis). Hill coefficients and oxygen half-saturation mean pressures ± SDs (n = 4) are indicated on the individual curves.

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