S/E binding in nuclear extracts from HA-1 cells incubated with 100 μM ZnCl₂ or 10 μM MPs for 24 hours.

The 12-bp oligomer (S/E) from the mouse HO-1 gene DE2 enhancer region has 85% similarity to the consensus sequence for an SP-1 and Egr-1 overlapping binding site. Lane F, free probe; lane ZC, cells incubated with ZnCl₂; lane ZP, cells incubated with ZnPP; lane SP, cells incubated with SnPP; lane CP, cells incubated with CrPP.