Resolution of PTLD after CyA cessation in animal no. 13 629.

(A) Two-color staining and flow cytometry (CD3 versus PAA) of lymph node cells during PTLD (day 48) and following complete resolution of PTLD (day 69). PAA is a marker of donor-type cells (see “Results” and “Materials and methods”). Forward scatter (FSC), side scatter (SSC), pig allelic antigen (PAA). (B) Hematoxylin and eosin staining of mesenteric lymph node tissue taken on day 48 (top) and day 69 (bottom). Typical polymorphous PTLD with a mixture of immunoblasts, plasmacytoid cells, and plasma cells can be seen in the day 48 but not the day 69 sample (original magnification × 500).