Mobilization in monkeys with anti-CD18 alone, anti-VLA4 alone, or anti-CD18 in combination with anti-VLA4 at standard doses of 2 mg/kg.

The top panel shows WBCs and CFU-C per milliliter of blood from a monkey treated with 2 injections (arrows) of anti-CD18. The middle panel shows results representing the mean of 3 experiments with monkeys given 3 injections of the humanized anti-α4, and the monkey in the lower panel was given 2 injections of both the anti-β2 and humanized anti-α4 antibodies concurrently (dark arrows).