Fig. 1.
Fig. 1. Binding of antibodies to CHO cells expressing αIIbβ3 or αvβ3. / CHO cells, expressing either αIIbβ3 (left column) or αvβ3 (right column), were incubated with platelet-associated autoantibody from ITP patients (ITP-4, -5, -6) or allo-antibody from a patient with posttransfusion purpura (PTP-1), and bound antibody was detected by FACS analysis using FITC-antihuman IgG. In each panel, binding to CHO cells, expressing the glycoprotein complex (shaded profile), is compared to binding to native CHO cells (open profile).

Binding of antibodies to CHO cells expressing αIIbβ3 or αvβ3.

CHO cells, expressing either αIIbβ3 (left column) or αvβ3 (right column), were incubated with platelet-associated autoantibody from ITP patients (ITP-4, -5, -6) or allo-antibody from a patient with posttransfusion purpura (PTP-1), and bound antibody was detected by FACS analysis using FITC-antihuman IgG. In each panel, binding to CHO cells, expressing the glycoprotein complex (shaded profile), is compared to binding to native CHO cells (open profile).

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