Fig. 1.
Detection of KSHV vIL-6 and anti-KSHV antibody in sera from blood donors, HIV+ patients with or without KS, and patients with classic KS.
(A) The lower limit of ELISA sensitivity in serum samples was set at 300 pg/mL vIL-6. (B) IgG antibody for the whole KSHV lysate was determined by ELISA. Optical density (OD) ratios were determined by dividing the OD reading of each sample by cut-off value (average of negative control × 3). Samples with OD ratio of at least 1.0 were interpreted as positive. Dotted bars indicate the 75thpercentile for each group. Statistical significance of group differences was determined by the Mann-Whitney test.