Effect of anti-TRAIL mAb on apoptosis of PBMCs from AML patients and cord blood CD34⁺ cells following coculture with activated CD4⁺Vα24NKT cells derived from Pt 1.

Early apoptosis of the PBMCs from Pt 1 (M4) and Pt 4 (M1) and cord blood CD34⁺ cells was defined by AV⁺PI⁻ cells in the presence of anti-TRAIL mAb, RIK-2 (white column), or IgG1 isotype control (shadow column). The results are expressed as mean ± SD (n = 3) of the percentage of AV⁺PI⁻ cells.