Time course of neutrophil transmigration induced by IL-1β in PECAM-1–deficient and wild-type animals.

PECAM-1–deficient and wild-type mice were treated with intrascrotal saline or IL-1β (30 ng) 2, 4, and 24 hours before the cremaster muscle was prepared for intravital microscopy. The data represent mean ± SEM (n = 3 animals for 2- and 24-hour groups and n = 8 for the 4-hour group; ***P < .001).