Myeloid hyperplasia is inhibited by the presence of WT hematopoietic cells.

(A) WBC counts of reconstituted animals 1 and 6 months after transplantation. WT refers to animals that received only WT fetal liver cells, CD18 to animals that received only CD18-deficient fetal liver cells, and Mix to animals that received 50:50 mixtures of WT and CD18-deficient fetal liver cells. (B) Absolute neutrophil counts of reconstituted animals 1 and 6 months after transplantation. (C) Splenic weights of reconstituted animals 6 months after transplantation. *, increase in Mix is significant (P < .05) compared with WT at same time point. **, increase in CD18 is significant (P < .05) compared with WT or Mix at same time point.