Putative amino acid sequence of mouse B7-H1 and alignment with human B7-H1.

(A) Predicted amino acid sequence of mB7-H1 and alignment with human B7-H1. Signal peptide, IgV-like domain, IgC-like domain, transmembrane (TM), and cytoplasmic tail are indicated. (B) Alignment of mB7-H1 with other members of the B7 family. Conserved cysteine residues, which may be important to form the disulfide bounds of IgV and IgC domains, are marked by star signs. A few gaps (−) were introduced for the optimal alignment. Identical amino acid residues are shaded and conserved residues are boxed. The nucleic acid and amino acid sequences of mouse B7-H1 are available from GenBank under accession no. AAG31810.