Fig. 4.
TF-specific binding, internalization, and degradation of VIIa in BHK(TF), BHK(TFΔcyto), and BHK(TFC245S) cells.
Experiments were performed as described in Figure 1 with BHK(TF) (■), BHK(TFΔcyto) (▴), and BHK(TFC245S) (●). The data represent the cell surface–associated VIIa (A), internalized VIIa (B), and degraded VIIa (C). Data are the mean ± SD of 3 independent experiments in triplicate.