Fig. 1.
Comparison of fusion genes.
(A) Schematic representation of fusion genes. PNT indicates pointed domain; KD, tyrosine kinase domain; DNA, DNA-binding domain; ABD, actin-binding domain; tm, transmembrane domain; SH3: SRC homology 3; SH2, SRC homology 2. (B) Comparison of kinase domains of ARG, ABL, PDGFR, KIT, and JAK2.