IL-3 rescue of TEL/ARG-Ba/F3 cells and TEL/ABL-Ba/F3 cells.

(A) Growth curves for TEL/ARG-Ba/F3 cells treated with STI571 for 24 (░) and 72 hours (▪), respectively, and cultured in the absence or presence of 15% WEHI-conditioned medium, used as a source of IL-3 (left panel). Growth curves for TEL/ABL-Ba/F3 cells treated as described for TEL/ARG-Ba/F3 cells (right panel). Experiments were performed in duplicate for each cell line, and viability counts were determined by trypan blue exclusion and shown as percentage control. (B) Annexin-PI analysis of TEL/ARG-Ba/F3 cells (left panel) and TEL/ABL-Ba/F3 cells (right panel), treated as described in panel A.