Combination of a single SQ injection of SB-251353 after 0, 1, 2, 3, and 4 days of G-CSF treatment.

Blood CFU-GM was collected 15 minutes after a single SQ injection of 2.5 mg/kg PBS (░) or SB-251353 (▪). Blood was collected 16 hours after the last dose of G-CSF in the combination groups. Data are presented as the mean ± SEM CFU-GM per mL blood from a representative of 3 experiments with similar results. All combination SB-251353 and G-CSF values were significantly higher than G-CSF alone (P < .05). ●, G-CSF plus PBS; ○, G-CSF plus SB-251353.