Fig. 4.
Activation of MAPK-dependent transcription factors in myeloid leukemia cell lines.
Lysates of myeloid leukemia cell lines were subjected to SDS-PAGE followed by Western blotting with anti–c-Myc (A) and anti–CREB-1 (B) antibodies. Activated c-Myc and CREB-1/ATF-1 were detected with phosphospecific antibodies against activated c-Myc and CREB-1.