Fig. 7.
Flow cytometric analysis of human platelets in PB of NOD/SCID mice.
PB from a representative transplanted mouse (A), human (B), and untransplanted mouse (C) was labeled with monoclonal antibodies against human CD41a, human CD42b, and mouse CD61. Mouse immunoglobulin G1 was used as an isotype control (top plots) for antihuman antibodies. Mouse platelets are found in the right lower quadrant of each blot. Human platelets are present in the upper left quadrant. Red cells and debris appear in the lower left quadrant.