P-selectin expression and fibrinogen binding to platelets activated by echicetin-IgMκ.

Platelets were activated by echicetin-IgMκ or thrombin as positive control, and binding of anti–P-selectin antibodies (A) or FITC-fibrinogen (B) was measured. In comparison to resting platelets (1), both echicetin-IgMκ–activated (2) and thrombin-activated (3) platelets bind higher amounts of anti P-selectin antibodies and FITC-fibrinogen. All measurements were repeated with platelets from 3 different donors.