Fig. 2.
Anti-CD3 antibody-activated TK+ T cells are killed by GCV in vitro.
Spleen cells from B6 TK− and TK+ mice were activated in vitro with immobilized anti-CD3 antibody and IL-2 for 3 days. Cells were then transferred into fresh flasks and grown in IL-2 ± GCV (10 μg/mL). The total number of viable cells was monitored over the ensuing 5 days and is depicted for each of the groups.