Fig. 1.
pLL211/DNA complexes exhibit increased circulation in mice compared to pLL20/DNA complexes and are unaffected by the type of DNA used.
pLL/DNA complexes, formed with pLL20 (20 kd pLL/DNA) or pLL211 (211 kd pLL/DNA), and either DNAct(▪), DNAcp (■), or DNAlp (░) were administered to female Balb/c mice (0.1 mL of 10 μg/mL DNA) through tail vein injection. Administration of free DNA with radioactive probe is also shown (DNA). Mice were killed after 30 minutes, and the blood was assayed for 32P-levels. Results show the mean ± SD of 3 independent experiments.