Fig. 3.
Fig. 3. pLL20/DNA complexes, but not pLL211/DNA, show punctate distribution of radioactivity in blood smears, and both types of complexes bind erythrocytes. / pLL20/DNAct or pLL211/DNAct complexes were administered intravenously to female Balb/c mice (0.1 mL of 10 μg/mL DNA). Blood was sampled from the end of the tail after 1 minute and smeared onto glass slides. Radioactivity in the smear was developed by exposure of the slides to liquid photographic emulsion and viewed by light microscopy. (A) pLL20/DNAct (80 × magnification); (B) pLL211/DNAct (80 × magnification); (C) DNA alone (80 × magnification); (D) pLL20/DNAct (400 × magnification). Similar results were obtained using pLL/DNAcp complexes (data not shown).

pLL20/DNA complexes, but not pLL211/DNA, show punctate distribution of radioactivity in blood smears, and both types of complexes bind erythrocytes.

pLL20/DNAct or pLL211/DNAct complexes were administered intravenously to female Balb/c mice (0.1 mL of 10 μg/mL DNA). Blood was sampled from the end of the tail after 1 minute and smeared onto glass slides. Radioactivity in the smear was developed by exposure of the slides to liquid photographic emulsion and viewed by light microscopy. (A) pLL20/DNAct (80 × magnification); (B) pLL211/DNAct (80 × magnification); (C) DNA alone (80 × magnification); (D) pLL20/DNAct (400 × magnification). Similar results were obtained using pLL/DNAcp complexes (data not shown).

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