Fig. 4.
Fig. 4. pLL20/DNA and pLL211/DNA complexes associate with Kupffer cells in mice. / pLL20/DNAct or pLL211/DNAct complexes were administered intravenously to female Balb/c mice (0.1 mL of 10 μg/mL DNA). Liver sections were stained with hematoxylin (blue/purple nuclei) and the macrophage marker F4/80 (pink/red cytoplasm), and the radioactivity was viewed by exposure of the slides to liquid photographic emulsion for (A) 1 day or (B) 7 days. (i) pLL20/DNAct; (ii) pLL211/DNAct; (iii) DNA alone (note: DNA is washed from the slides during the development process). Similar results were obtained using pLL/DNAcp complexes (data not shown).

pLL20/DNA and pLL211/DNA complexes associate with Kupffer cells in mice.

pLL20/DNAct or pLL211/DNAct complexes were administered intravenously to female Balb/c mice (0.1 mL of 10 μg/mL DNA). Liver sections were stained with hematoxylin (blue/purple nuclei) and the macrophage marker F4/80 (pink/red cytoplasm), and the radioactivity was viewed by exposure of the slides to liquid photographic emulsion for (A) 1 day or (B) 7 days. (i) pLL20/DNAct; (ii) pLL211/DNAct; (iii) DNA alone (note: DNA is washed from the slides during the development process). Similar results were obtained using pLL/DNAcp complexes (data not shown).

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