Fig. 8.
Overexpression of BiP in CHO-IIIa cells cotransfected with normal and mutant GPIIb.
CHO-IIIa cells were cotransfected with different proportions of normal and mutant [674R]GPIIb cDNAs, as described in Figure 6, and 4μg of the BiP cDNA or the void plasmid. Forty-eight hours after transfection, the surface exposure of GPIIb-IIIa was analyzed by flow cytometry with the anti-GPIIb moAb M3. The results are the means ± SEM of at least 3 independent experiments in duplicate.