Fig. 1.
Whole blood coagulation and TRAP.
Comparison of whole blood coagulation in the absence (▪) and presence (●) of 5μM TRAP. Coagulation was initiated in whole blood by 25 pM relipidated TF as described in “Materials and methods.” Panel A represents thrombin (TAT) generation, panel B platelet activation (osteonectin [ON] release). Arrow “a” indicates clotting times for the control experiment, arrow “b” for the TRAP experiment.