Fig. 3.
Whole blood coagulation and ASA.
Comparison of whole blood coagulation before (▪) and after (●) administration of ASA, 2 × 325 mg/d for 3 consecutive days. Coagulation was initiated in whole blood by 25 pM relipidated TF as described in “Materials and methods.” Panel A represents thrombin (TAT) generation, panel B fibrin (FPA) formation, and panel C platelet activation (osteonectin [ON] release). Arrow “a” indicates clotting times before ASA administration, arrow “b” after.