Fig. 5.
![Fig. 5. Whole blood coagulation and 7E3. / Comparison of whole blood coagulation in the absence (▪) and presence (●) of 7E3 (10 μg/mL). Coagulation was initiated in whole blood by 25 pM relipidated TF as described in “Materials and methods.” Panel A represents thrombin (TAT) generation, panel B fibrin (FPA) formation, and panels C and D platelet activation (osteonectin [ON] and PF4 release, respectively). Arrow “a” indicates clotting times for the control experiment, arrow “b” for the 7E3 experiment. Upper lane in panel D represents control experiment and lower lane represents 7E3 experiment.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/97/8/10.1182_blood.v97.8.2314/5/h80810935005.jpeg?Expires=1735516498&Signature=x11Jliwv947QPP35rLpj7nPutnFjDsrChmyRA13EWkua6o2kG9Yb9ymzqJHhM2-jidYTrdDz6eA2nVdaElP-IlXoSPLPMpY0qWQ-j~PV34r-6jby9DNhgkm8fz~CjcgpZuP5O02i1r9EZ4Hxz7-aP4nynClPdlcGGsNjbkyFbjH28vA-YzD8qGoGjVW4XfRHDGNgjTfif0KkP2LkdLzPrGbVNbAI9iuDgGz5CBmP5ECq7a-4~~1knqez4wr13YLhCF3lQosRITMjxO~7WkP8uk71gTi9rLPRASsSmXltwBrVcoRdOWvKO7yRlkeMk9iGfGWY3~5b8kxY6mU-CfWtDA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Whole blood coagulation and 7E3.
Comparison of whole blood coagulation in the absence (▪) and presence (●) of 7E3 (10 μg/mL). Coagulation was initiated in whole blood by 25 pM relipidated TF as described in “Materials and methods.” Panel A represents thrombin (TAT) generation, panel B fibrin (FPA) formation, and panels C and D platelet activation (osteonectin [ON] and PF4 release, respectively). Arrow “a” indicates clotting times for the control experiment, arrow “b” for the 7E3 experiment. Upper lane in panel D represents control experiment and lower lane represents 7E3 experiment.
