Kaplan-Meier estimates of EFS for patients undergoing allogeneic bone marrow transplantation.

(A, C) Low-risk patients (n = 64) and (B) high-risk patients (n = 49) were divided into subgroups based on the numbers of CD4^bright DC cells (A, B) and CD34⁺ cells (C) in the graft. Integer values of cells/kg (×10⁵) were chosen as boundaries between subgroups to yield similar-sized populations for each parameter. Subgroups based on CD4^bright DC content were defined as less than 0.6 × 10⁶ cells/kg (group 1_(DC), n = 35); 0.6 to 0.9 × 10⁶ cells/kg (group 2_(DC), n = 38); and more than 0.9 × 10⁶ cells/kg (group 3_(DC), n = 40). Subgroups based on CD34⁺ cell content were defined as less than 2.5 × 10⁶ cells/kg (group 1_(CD34), n = 41); 2.5 to 3.5 × 10⁶cells/kg (group 2_(CD34), n = 33); and more than 3.5 × 10⁶ cells/kg (group 3_(CD34), n = 39). In each panel, Kaplan-Meier curves for actuarial EFS are shown according to subgroups, with surviving patients represented as symbols: group 1 (▿), group 2 (■), and group 3 (○).