IFN-α–mediated apoptosis in Daudi cells.

Effect of CPP32-inhibitor (0.5 μM), recCD95:Fc (25 μg/mL), anti-CD95L antibody (5 μg/mL), anti–TNF-α antibody (100 ng/mL), sTNF RI (100 ng/mL), ICE-inhibitor I (100 nM), anti-CD95 IgG (5 μg/mL), and anti-CD95 IgM (100 ng/mL) antibodies on IFN-α–mediated apoptosis in Daudi cells. Inhibition and enhancement were calculated as reduction or increase of apoptosis compared to apoptosis of IFN-α–treated cells set as 100%. Cells were cultured for 3 days and collected, and percentage apoptosis was determined by morphology. Results represent median values from at least 4 experiments.