Trx80 induces expression of CD14, CD40, CD54, and CD86 on purified human CD14⁺ monocytes.

Purified CD14⁺ monocytes were stimulated with either Trx, Trx80, or IL-2 and grown for 3 days in ultralow attachment plates. Harvested cells were analyzed for expression of CD14 (A), CD40 (B), CD54 (C), and CD86 (D). The MFI from 5 different donors is shown in black dots with the median value indicated with a black bar. There was a significant increase in the expression of these markers when monocytes were stimulated with 100 nM and 1 μM Trx80 compared to unstimulated cells, which is indicated with P values in the figure.