General features of the spleens from adult (6 to 12 months of age) GATA-1^low and wild-type mice.

Photographic picture (on the right), weight (top on the left) and total number of cells (TNC, bottom on the left) of spleens from untreated (intact), day-3 PHZ-treated, and day-6 EPO-treated wild-type (white bars) and GATA-1^low (gray bars) mice. The values are reported as the mean ( ±  SD) of replicate measures. The number on each bar indicates the number of mice analyzed for that experimental group. The values observed in the GATA-1^low mice are statistically different from those observed in the corresponding wild-type animals. §P < .05; §§P < .01.