Fig. 1.
![Fig. 1. Fever-range WBH causes lymphocyte redistribution in lymphoid tissues. / After WBH treatment of BALB/c mice for 6 hours (core temperature, 39.8 ± 0.2°C), the total number of lymphocytes in lymphoid organs (peripheral blood [PB], PLN, and spleen) was quantified. L-selectin and α4β7 integrin expression on tissue lymphocytes was analyzed by flow cytometry. Values represent the mean ± SE of 3 independent experiments. Analysis by unpaired 2-tailed Student t test showed that the difference between the number of lymphocytes in PB and PLN of normothermic controls (37.1 ± 0.2°C) and WBH-treated mice was significant (* indicates P < .02 and **,P < .03).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/97/9/10.1182_blood.v97.9.2727/6/h80910963001.jpeg?Expires=1735526037&Signature=EYFOCIbD4AXU0UFr4KPDJ4rQSob1RXc4dzgz6H4yVfy0R1fibs-bPNbqPNblMQLFSgfk9Ml2CHSyQkctOmFLJ0F5RTS232fWM5lzK8EXYFKIisC5nRWE20Fwxra1H22u37VxD7mopSzHBi3hjip~7ia7d2dMyz2okRECFXdjFdHLTJ7IM491za8fd9VWkwuNNI6K4W6~Jt4bf31T~oNIhpH4KfuFhdM5dQFIu4jVlaoH7ubJ6npzcxL72M4GXA4RGMLwg4H21hjNcxokEHPVntlLjmq7tk~eEqX~D~z7z~slLUsMH8rJwWORsyWcpKs9wexsvwJxgAs89a6wafDaNA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Fever-range WBH causes lymphocyte redistribution in lymphoid tissues.
After WBH treatment of BALB/c mice for 6 hours (core temperature, 39.8 ± 0.2°C), the total number of lymphocytes in lymphoid organs (peripheral blood [PB], PLN, and spleen) was quantified. L-selectin and α4β7 integrin expression on tissue lymphocytes was analyzed by flow cytometry. Values represent the mean ± SE of 3 independent experiments. Analysis by unpaired 2-tailed Student t test showed that the difference between the number of lymphocytes in PB and PLN of normothermic controls (37.1 ± 0.2°C) and WBH-treated mice was significant (* indicates P < .02 and **,P < .03).
