Fig. 3.
Suppression of IL-12 p70 production by fMLP and T-20 peptide is reversed by pertussis toxin.
Monocytes were cultured for 4 hours with 250 ng/mL pertussis toxin (▩) and then stimulated with SAC and IFN-γ in the presence or absence of fMLP (10−5 M) or T-20 peptide (10−5 M). ■, control. IL-12 p70 concentrations were measured 24 hours after stimulation by ELISA. Data are mean ± 1 SD from the monocytes of 3 separate donors (*P < .05; **P < .01). ND, not detected.
