Pathologic findings in glomeruli of MRL/lpr mouse kidneys.

A nontreated MRL/lpr mouse (20 weeks old) shows the proliferation of mesangial cells in the glomerulus (A) and marked IgG deposits (B). A MRL/lpr mouse (60 weeks old) treated with 5.5 Gy × 2 + IBM shows normal appearance (C) without C3 deposits (D) 40 weeks after the treatment.