Inverse correlation between CD4 counts and circulating IL-7 levels during chemotherapy-induced CD4 lymphopenia.

Scatter plot of serum IL-7 level and CD4 count in children and young adults with solid tumors at presentation (n = 30), during chemotherapy (n = 17), and 6 to 9 months after completing therapy (n = 12). Spearman correlation (r) and P value are shown with each graph. Normal IL-7 ranges for adults ± SD 2 are shaded.