Amino acid sequence homology of human P5′N-1 to similar proteins.

Dash indicates gaps in the aligned sequences, and x indicates amino acids identical to those in the equivalent position of the wild-type human protein. Residue Asp98 (boxed) is mutated to Val in the Norwegian family. Aligned sequences are Mus musculus (derived from EST databases), D. melanogaster (CG3362 gene product), Caenorhabditis elegans (hypothetical protein F25B5.3), and Arabidopsis thaliana (AAC67350.1).