Fig. 7.
In vivo clearance of 6-19J and L8D IgG3 mAbs.
Half a milligram each mAb (○, 6-19J; ●, L8D) was injected intravenously into immunoglobulin-deficient μMT mice (3 mice per group). Blood samples were collected at the time points indicated. The amount of each mAb remaining in blood was calculated relative to the value 1 minute after the injection. Error bars (± 1 SD) are shown only on last points; fractional errors of other points are similar or lower.