Normal phosphorylation of STAT1 in mature FA-C fibroblasts.

Immunoblot analysis of human FA-C fibroblasts by means of an antibody specific for phosphorylated STAT1 demonstrates that STAT1 is phosphorylated equivalently between mutant and corrected IFNγ-stimulated cells (1 ng/mL IFNγ) (top panel). In addition, total STAT1 is expressed at approximately equal levels (bottom panel).