Leukemic blast cell infiltration, bone marrow microvessel density and peripheral blood cell counts.

(A) Leukemic blast cell infiltration determined by cytologic analyses (○) and bone marrow microvessel density (●) during the course of the disease and different antileukemic treatments. Duration of the treatment with mitoxantrone/etoposide (Mitox/Etop), thalidomide (Thalid), and SU5416 is indicated at the top of the figure. D represents values obtained at initial diagnosis; CR, values obtained at the time of complete remission. (B) Platelet (○) and neutrophil counts (●) during different treatments of the patient's second AML relapse.