Subject maximum CMV titer and local tree pollen levels for spring 1999 demonstrate association of CMV reactivation and local pollen level.

The maximum CMV DNA levels observed for each subject throughout the monitoring and collection/treatment phases and local tree pollen counts are shown for Norfolk and Denver (each subject shown once—minimum detection level of 100 GE/mL). Twenty Norfolk CMV seropositive subjects were entered into the monitoring phase March 2 to 30 and followed for a maximum of 65 days, through May 5. Twenty-five Denver CMV seropositive subjects were entered into the monitoring phase March 15 to April 23 and followed for a maximum of 120 days, through July 7. Norfolk subjects reactivated during April and Denver subjects during June/July. Denver had several short-lived increases in tree pollen throughout the spring, but the largest, sustained period immediately preceded the subject CMV titer rise. Key: Norfolk subjects, (●); Norfolk tree pollen, (—) ; Denver subjects (■); Denver tree pollen, (– – –).