Graft-facilitating effect of irradiated human PBMCs.

BALB/c (H-2^d) mice were submitted to 6-Gy TBI and grafted 24 hours later with 10⁶ BM cells from FVB (H-2^q; panel A, 2 independent experiments with 12 mice per group) or C57BL/6 (H-2^b; panel B, one experiment with 12 mice per group) mice alone or with 10⁷ γ-irradiated human PBMCs. Between day 45 and day 50 post-BMT, engraftment was measured by FACS analysis. Results are expressed as previously described in Figure3. **P < .005.