Fig. 6.
Proliferative responses to a series of GPIIb-IIIa preparations in GPIIb-IIIa–reactive CD4+ T-cell lines.
GPIIb-IIIa–reactive T-cell lines were cultured with autologous antigen-presenting cells in the presence or absence of various antigens, including tetanus toxoid, mock-treated PBS containing trypsin alone, native GPIIb-IIIa, trypsin-digested GPIIb-IIIa, GST, or individual recombinant GPIIb-IIIa fragments for 7 days, and3H-thymidine incorporation was measured by liquid-scintillation counting. Only standard deviation > 20% of the mean and 100 cpm is shown as an extended line above a bar.
