Perturbed distribution of CD11c⁺ spleen DCs in some donors.

Double staining for nuclei (Hoechst, A,C,E) and CD11c (Texas Red, B,D,F). Original magnification, ×200. (A, B) Donor 147 showing a normal distribution of CD11c⁺ DCs around the edge of the white pulp and scattered CD11c⁺ DC around the arteriole (A). (C,D) Donor 106. (E,F) Donor 93. CD11c⁺ cells are concentrated in the white pulp in proximity to arterioles.