Restoration of CSF-1–dependent F4/80⁺ macrophage populations in

Csf1^op/Csf1^opmice expressing TgC. Tissues were subjected to immunostaining with the macrophage-specific monoclonal antibody F4/80. Sagittal sections of 3-month-old knee joints, showing bone marrow (BM) and periosteum (PO) (A-C) and synovial membrane (SM) (D-F). Longitudinal section of 2-week-old tibia, showing tendon (TD) (G-I), transverse sections of 2-week-old testes (J-L), and transverse sections of 3-month-old mouse sublingual salivary gland (M-O; panel M counterstained). Arrows point to regions of F4/80⁺staining. Bar: 50 μm.