Fig. 1.
Stereo ribbon diagram of the factor VIII C2-domain/BO2C11 Fab complex.
The light chain, heavy chain, and C2 domain are displayed in blue, magenta, and green, respectively. The BO2C11 Fab displays a typical immunoglobulin fold with 18 β strands in the light chain and 19 β strands in the heavy chain. Two β hairpins from the C2 domain project into the CDR loops of the Fab fragment.