Fig. 1.
Fig. 1. Peroxynitrite is produced by the reaction of O2•− with NO•. / NO• is produced by NOSs that utilize L-arginine and oxygen to form NO• and citrulline. SOD catalyses the dismutation of O2•− radicals. Peroxynitrite induces tyrosine nitration in vivo. Thus, the peroxynitrite concentration is mainly regulated by SOD and NOS.

Peroxynitrite is produced by the reaction of O2•− with NO•.

NO• is produced by NOSs that utilize L-arginine and oxygen to form NO• and citrulline. SOD catalyses the dismutation of O2•− radicals. Peroxynitrite induces tyrosine nitration in vivo. Thus, the peroxynitrite concentration is mainly regulated by SOD and NOS.

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