Antigen-specific CD8 T cells for HIV, CMV, and EBV uniformly do not express CCR7.

The proportion of tetramer⁺ CD8 T cells that stained for CCR7, CD62L, and CD45RA is shown for samples from 12 HIV-infected donors and 6 healthy donors who had recognition of at least one of the tetramers listed in Table 1. Expression of CCR7 and CD62L was similar in HIV and other viral-specific cells and in samples from HIV-seropositive donors and healthy donors. However, CD45RA was conspicuously not expressed only in HIV-specific CD8 T cells.