Fig. 3.
CLL cells infected with hf-HSVB7.1 are more efficient at stimulating T-cell proliferation than HSVB7.1-transduced cells.
CLL cells were left untreated (mock infected) or transduced with equivalent transduction units of HSVlac, hf-HSVlac, HSVB7.1, or hf-HSVB7.1. ▪ indicates PMA was added to the reaction at a final concentration of 10 ng/mL, whereas ■ indicates the absence of PMA. [3H]-thymidine uptake data are expressed as counts per minute (cpm). Error bars represent standard deviation. Asterisks indicate statistically significant differences (P < .001) as determined by single-factor analysis of variance. Data are representative of 4 different patient samples.